TRH is produced by the globe in medial neurons of the paraventricular nucleus.
2.
Activation of the median preoptic nucleus leads to stimulation of the paraventricular nucleus ( PVN ).
3.
CRH is secreted by the paraventricular nucleus ( PVN ) of the hypothalamus in response to stress.
4.
These neurons project to the supraoptic nucleus and paraventricular nucleus to regulate the activity of vasopressin-secreting neurons.
5.
Early life stress is correlated with hyper-phosphorylation of the MeCP2 protein in the paraventricular nucleus of the hypothalamus.
6.
Most of the circulating oxytocin and vasopressin hormones are synthesized in magnocellular neurosecretory cells of the supraoptic nucleus and paraventricular nucleus of the hypothalamus.
7.
Thus, glutamate bound to receptors is necessary for the activation of these neurons in the median preoptic nucleus and the activation of the paraventricular nucleus.
8.
Cirazoline has also been shown to decrease food intake in rats, purportedly through activation of ? 1 adrenoceptors in the paraventricular nucleus in the hypothalamus of the brain.
9.
There is a high expression of GPER, as well as ER?, in oxytocin neurons in various parts of the hypothalamus, including the paraventricular nucleus and the supraoptic nucleus.
10.
Stimulation of 5-HT 2C receptors leads to increase of corticotropin releasing hormone ( CRH ) and vasopressin mRNA in the paraventricular nucleus and proopiomelanocortin in the anterior pituitary lobe.
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